About The Science

How incretin drugs work, drawn out: incretin physiology, GIP versus GLP-1 receptor effects, gastric emptying, appetite circuits, why weight returns, lean mass, cardiovascular outcomes from SELECT, kidney outcomes from FLOW and sleep apnea from SURMOUNT-OSA. Includes an interactive mechanism diagram.

What this site is

The Science (formblendsscience.com) is one of a small network of single-subject publications run by FormBlends. Each site in the network covers one slice of the GLP-1 and peptide topic in depth, so that a reader with a specific question lands on a page built for that question rather than a general overview. This site's slice: How incretin drugs work, drawn out: incretin physiology, GIP versus GLP-1 receptor effects, gastric emptying, appetite circuits, why weight returns, lean mass, cardiovascular outcomes from SELECT, kidney outcomes from FLOW and sleep apnea from SURMOUNT-OSA. Includes an interactive mechanism diagram.

Who runs it

The site is written and maintained by the FormBlends editorial team, the same team that publishes formblends.com. FormBlends operates a GLP-1 weight-loss program that dispenses compounded medication through licensed pharmacies. That is a commercial interest and you should read the site with it in mind. Where a page links to a FormBlends product or report, the link is marked as such.

Editorial process

• Every number is traced to a primary source: a PubMed-indexed paper, an FDA label or Drugs@FDA record, an FDA announcement with a date, or a manufacturer page with an access date. If a number cannot be sourced it is not published.
• Calculators are pure arithmetic. The formula and the assumptions sit under every tool, with the date the assumptions were last checked. The maths is covered by automated tests.
• Pages carry an updated date. When a label, a price or a trial result changes, the page is revised and the date moves.
• No reviews, testimonials, star ratings, or named clinicians. We do not claim medical review that did not happen.
• Compounded drugs are described as what they are: not FDA approved, not interchangeable with brand products, and dispensed under a prescription.

What this site is not

It is not medical advice, and it is not a substitute for a prescriber or pharmacist. Nothing here decides a dose, an eligibility, or a treatment. See the medical disclaimer.

Contact

Corrections and questions reach the editorial team through formblends.com. Please quote the page URL and the number or sentence in question.